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October 2014

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Randomised controlled trials for testing Ebola treatments are unethical say experts
A group of leading health experts have urged the deployment of alternative trial designs to fast-track the evaluation of new Ebola treatments to suit the urgency of the crisis. 15 Oct 2014

Scripps scientists create cholesterol-like molecule that reduces artherosclerosis
Scientists at The Scripps Research Institute (TSRI) in the US have synthesised a molecule that mimics high-density cholesterol and shown it can reduce plaque build-up in arteries even when taken orally. 15 Oct 2014

Exco InTouch first to comply with HIPAA, Safe Harbor and EU data protection rules
Exco InTouch has announced that it has become the first clinical research solutions provider to comply with the Safe Harbor, EU Data Protection and HIPAA (Health Insurance Portability and Accountability Act) regulations governing security and data privacy for patients. 15 Oct 2014

Auspherix and Domainex collaborate to combat drug-resistant bacteria
Cambridge-based Domainex Ltd and University of Technology Sydney spinout Auspherix Pty Ltd have announced a collaboration that will develop Auspherix’s novel anti-infective drug discovery programme towards the nomination of a clinical candidate. 15 Oct 2014

Karolinska Development appoints new CEO
Swedish medical technology company Karolinska Development has announced that Bruno Lucidi has been appointed as permanent CEO from today, in addition to existing positions in the company. 15 Oct 2014

Replikins Global Surveillance System claims current Ebola outbreak could have been predicted two years ago by monitoring genomic changes in the virus

CFI Medical awarded CE mark for Zero-Gravity radiation protection system
CFI Medical has received the CE mark for its Zero-Gravity Suspended Radiation Protection System Floor Unit for protecting clinicians when using X-rays in operating theatres. 14 Oct 2014

LoneStar receives CE mark for hydrogel implant for heart-failure treatment
California-based LoneStar Heart, Inc. has announced that it has received the CE Mark for its Algisyl-LVR hydrogel implant, the company’s lead product for the treatment of advanced heart failure. 14 Oct 2014

New Oncology and Gustave Roussy collaborate on genetic testing of tumours
Cologne-based cancer diagnostics developer New Oncology has announced that it has entered into a collaboration agreement with Gustave Roussy Cancer Campus, a research institute based in Paris. 14 Oct 2014

Lung cancer can stay dormant for 20 years until triggered by genetic faults
Researchers at Cancer Research UK have discovered that lung cancers can lie dormant for over 20 years until genetic faults trigger sections to grow and the cancer becomes aggressive. 13 Oct 2014

Genetic test identifies people at higher risk of atrial fibrillation and stroke 
People who are genetically predisposed to develop atrial fibrillation, which increases risk of stroke, can be identified with a blood test according to research at Lund University in Sweden. 13 October 2014

Novartis announces collaboration to evaluate Bristol-Myers Squibb's novel immunotherapy drug
The collaboration will evaluate the safety, tolerability and preliminary efficacy of three molecularly targeted compounds in combination with Bristol-Myers Squibb's investigational PD-1 immune checkpoint inhibitor, Opdivo. 9 Oct 2014

European Commission announces first SMEs to benefit from €3bn innovation fund 
The European Commission has published a list of the 155 Small and Medium-sized Enterprises (SMEs) that will be the first to benefit from its new 'SME Instrument' funding stream. 9 Oct 2014

Adaptimmune secures a further US$104m investment for product development
Oxford-based therapeutics company Adaptimmune Limited, has announced the completion of a US$104m series A financing round to advance its programmes into the clinic in multiple cancer indications. 9 Oct 2014

Paris Public Hospitals Group and Magnisense partner to develop tests for cardiovascular diseases
French hospital group AP-HP, (Assistance Publique-Hôpitaux de Paris), and diagnostics technology developer Magnisense have signed a partnership agreement to develop rapid portable diagnostic tests for cardiovascular diseases. 9 Oct 2014

Nobel prize for chemistry awarded to inventors of nanoscale optical microscope
The Nobel Prize in Chemistry 2014 has been awarded jointly to Eric Betzig, of the Howard Hughes Medical Institute, USA; Stefan W. Hell of the Max Planck Institute for Biophysical Chemistry and the German Cancer Research Center; and William E. Moerner of Stanford University, USA. 8 Oct 2014

New model gives 3D reconstruction of the brain's memory structures
Researchers at Ruhr-Universitaet-Bochum have developed a new method for creating 3D models of memory-relevant brain structures. They published their results in the journal Frontiers in Neuroanatomy. 7 Oct 2014

Scientists at UCL and NTNU awarded Nobel Prize for discovering brain's positioning system 
The 2014 Nobel Prize in Physiology or Medicine has been awarded to Professor John O’Keefe of University College London and husband-and-wife team Professors May-Britt Moser and Edvard Moser of the Norwegian University of Science and Technology. 6 Oct 2014

Massively parallel approach to stem cell culture will accelerate research
Plasticell has announced the publication of research on the company’s high throughput 'Combinatorial Cell Culture' (CombiCult) technology that allows a single scientist to carry out 10,000 stem cell experiments in parallel. 6 Oct 2014

Low carbohydrate diet improves physical and general health of diabetes patients
A low-carbohydrate diet has a good effect not only on blood glucose, but also on physical functions, bodily pain and general health, according to a two-year study at Linköping University.

UCL awarded £15m to train bioscience PhDs
The UK Biotechnology and Biological Sciences Research Council (BBSRC)has awarded University College London (UCL) £15m to support thirty PhD studentships annually for the next five years in ... . 6 Oct 2014

Specific molecular structure indicates if a drug is likely to be safe for clinical use
A test developed at the University of Manchester helps determine which  drugs are unlikely to work because of their molecular structure. This is likely to greatly speed up the time it takes to make safe and effective medicines available and reduce costs of drug discovery. 6 Oct 2014

Exco InTouch shortlisted for SCRIP Award
Exco InTouch has announced that its mDNA technology project team have been shortlisted for the “Best Technological Development in Clinical Trials” category for the 2014 SCRIP Awards. 3 Oct 2014

Stem cells discovered in layer behind cornea could treat blindness
Scientists at the University of Southampton have discovered that a region at the front of the eye harbours special stem cells that could treat degenerative retinal diseases. 2 Oct 2014

New forecasts show Ebola infections could reach 1.4 million by January
The current Ebola epidemic could claim hundreds of thousands of lives and infect more than 1.4 million people by the end of January 2015, according to a new forecast released by the US CDC. 2 Oct 2014

Scale of current Ebola outbreak makes previous models for predicting spread  useless
A mathematical model that replicates and forecasts Ebola outbreaks is no longer suitable for predicting the eventual scale of the current epidemic, according to researchers at the University of Warwick. 2 Oct 2014

September

Tenth of antibiotics prescribed by GPs over 22 years fail to cure patients
A 22-year study by Cardiff University has found that more than one in 10 of all antibiotic treatments in a primary care setting failed. This rate has increased and continues to rise. 26 Sept 2014

AstraZeneca and Cancer Research UK establish Cambridge lab to develop cancer drugs
MedImmune, the global biologics research and development arm of AstraZeneca and Cancer Research UK, with its commercial arm, Cancer Research Technology (CRT), are establishing a joint laboratory in Cambridge, UK to study novel biologic cancer treatments. 26 Sept 2014

University of Pittsburgh awarded $5.8m to develop 3D microfluidic model of the liver
The University of Pittsburgh School of Medicine has won $5.8 million grant from the National Institutes of Health (NIH) to further develop a microfluidic 3D model system that mimics the structure and function of the liver. 26 Sept 2014

Invest in Photonics chooses 20 European companies to pitch for €70m funding
Invest in Photonics 2014, a two-day international business partnering convention for photonics VC investment, has announced the selection of 20 emerging technology companies from around Europe to participate in a special funding session. 23 Sept 2014

Mayden awards contract to HealthMotive for NHS Spine integration software
Cloud solution developer Mayden has entered into a contract with healthcare systems developer  HealthMotive to incorporate HealthMotive’s Spin Messaging Handler (SMH) product into Mayden’s product offering. 23 Sept 2014

Sheffield displays the latest in robotics in Festival of the Mind
The University of Sheffield is holding a unique series of lectures between 19-25 September, focusing on the latest advancements in robotics and what the future has in store. 19 Sept 2014

electroCore to present at European headache meeting on non-invasive vagus nerve stimulation therapy for cluster headache
The company will be presenting full data on their PREVA study, a randomized, multi-centre trial across several European countries at the EHMTIC meeting in Copenhaghen. 18 Sept 2014

Exco InTouch selected to present on mHealth innovation at HealthXL event in San Francisco
The company is presenting on its role as a key innovator in digital patient engagement and data capture solutions for clinical research at the HealthXL conference. 18 Sept 2014

International Ebola response "Totally, and lethally inadequate" says MSF
The International President of Médicins Sans Frontières (MSF), Dr Joanne Liu, has told the UN that the world must act now to fight Ebola or many more people will die and that the response remains totally and lethally inadequate. 17 Sept 2014

Open Bionics 3D printed prosthetic hand reaches global finals of Intel competition
Robotics startup Open Bionics has seen its idea to significantly reduce the cost of prosthetic limbs by using 3D printing reach the global final of Intel's Make it Wearable Competition. 11 Sep 2014

QuantuMDx announces prototype handheld lab for rapid DNA diagnostics
Newcastle-based medical device developers QuantuMDx Group has announced the successful production of their first fully-integrated sample-to-result working prototype of Q-POC, a handheld lab that delivers DNA-based medical diagnosis in minutes. 11 Sep 2014

NHS information exchange backbone rebuilt and upgraded
NHS Spine, a set of applications, services and directories that underpin information exchange across the NHS in England, has been successfully rebuilt in a project led by the Health and Social Care Information Centre. 11 Sep 2014

Regions most at risk of Ebola mapped
An international team of researchers has mapped the regions in Africa most at risk of an Ebola outbreak based on animal infections. 9 Sept 2014

New technique to test for prostate cancer
A team of researchers at Guangdong Medical College in China has demonstrated the potential of a new test to detect prostate cancer combining surface-enhanced Raman scattering (SERS) with a new technique called support vector machine (SVM). 9 Sept 2014

Ultrathin coronary stent with biodegradable coating shows promise
A new generation of coronary artery stent that combines a biodegradable component with an ultrathin metal scaffold showed promising results compared with the current gold standard stent in a large study. 9 Sept 2014

New model predicts best distribution of AEDs to treat heart failure in public places
A new method to predict the optimal number and location of automated external defibrillators (AEDs), to treat members of the public suffering heart attacks, has been developed in Paris. 8 Sept 2014

Sugar in diet depletes good cholesterol
Scientists at the University of Warwick have discovered that the ‘good’ form of cholesterol, HDL, is degraded by a sugar-derived substance in the body. 8 Sept 2014

Roche launches automated molecular diagnostic systems for blood and blood plasma screening
Roche has launched two integrated and fully automated molecular testing systems for blood and plasma donor screening, the cobas 6800 and 8800, based on Nobel-prize winning PCR technology. 2 Sept 2014

Exco InTouch achieves a first with mobile health apps for iOS, Android and Windows8
Exco InTouch has announced the availability of electronic clinical outcomes assessment (eCOA) apps on all three mobile operating platforms (iOS, Android and Windows8). 2 Sept 2014

Medtronic acquires Sapiens Steering Brain Stimulation for $200m
Medtronic has announced that it has acquired privately held Dutch company Sapiens Steering Brain Stimulation for approximately $200 million in an all-cash transaction. The deal strengthens Medtronic's capabilities in the modulation of brain function. 2 Sept 2014

Boston Scientific takes over Bayer's vascular disease business for 300m
Boston Scientific Corporation and Bayer Healthcare have announced the closure of the previously announced agreement for Boston Scientific to  purchase the Interventional business of Bayer Healthcare. 2 Sept 2014

3D printing in reconstructive facial surgery hindered by reimbursement challenge
The 3D printing sector is battling to convince surgeons that it is a financially viable treatment for craniomaxillofacial (CMF) reconstruction, despite it being lauded as a game-changing development, says an analyst with research and consulting firm GlobalData. 1 Sept 2014

August 2014

Nose cartilage cells can repair knee cartilage damage
Cells taken from the nasal septum are able to adapt to the environment of the knee joint and can thus repair articular cartilage defects, according to researchers at the University and the University Hospital of Basel. 29 Aug 2014

Avatars help deaf people to understand online text and interact with websites
Computer scientists from Saarbrücken, Germany are developing animated online characters to display text from web pages in sign language. and help deaf people communicate on online platforms via sign language. 29 Aug 2014

Remote monitoring of heart failure patients via implants halves mortality
BIOTRONIK has announced that a clinical trial of its implant-based remote monitoring system has lead to significant clinical benefits for heart failure patients. 29 Aug 2014

Almac Group to invest £54m over five years in Northern Ireland
Enterprise, Trade and Investment Minister for Northern Ireland Arlene Foster has announced that the Almac Group is investing over £54 million and creating 348 high quality jobs over the next five years. 29 August 2014

Exco InTouch achieves ISO9001:2008 certification
The certification recognises that the company has developed and implemented a quality management system built around processes of the highest standards. 29 Aug 2014

Ablynx awarded €2.1m to develop nanobody treatment for eye disease
Ghent-based Ablynx has been awarded a €2.1 million grant by the Flemish Agency for Innovation by Science and Technology (IWT) to develop the use of nanobodies for a novel approach to the treatment of diseases of the eye. 29 Aug 2014

Electronic cigarette use by youths doubles likelihood of going on to smoke tobacco
Youths who have used e-cigarettes are more likely to report that they may try conventional cigarettes, according to a study by Georgia State University and the US CDC. 29 Aug 2014

Haemostasis management device used in Afghanistan war zones approved by NICE
The ROTEM point of care blood analyser which has been used to manage major bleeding in soldiers in Afghanistan has now been recommended by NICE for use by the NHS. 29 Aug 2014

Primerdesign announces lowest cost DNA analytics device for health, veterinary, food and biothreat testing
Southampton University spinoff Primerdesign Ltd has announced the launch of what it claims is the world’s most affordable device for DNA diagnostics. The genesig q16 uses real-time PCR analysis to test DNA using a range of over 400 testing kits

Twelve NHS hospitals use 3D printing to test implants for reconstructive surgery
Stratasys Ltd has announced that UK medical 3D printing specialist, Replica 3DM, is using its Stratasys 3D Printers to provide a service to twelve NHS hospitals to print models for the validation of reconstructive implants prior to surgery. 26 Aug 2014

Edmond De Rothschild Investment Partners sells protein therapeutics investment to Johnson & Johnson company
Paris based Edmond De Rothschild Investment Partners (EdRIP) has announced that  one of its portfolio companies, Covagen A.G., has been acquired by Swiss company Cilag GmbH International, an affiliate of the Janssen Pharmaceutical Company, which is one of the Johnson & Johnson Family of Companies. 26 Aug 2014

Genetically modified bacteria safely kill cancer cells when injected directly
A modified version of the soil bacterium Clostridium novyi can produce a strong and precisely targeted anti-tumour response in rats, dogs and humans when injected directly, according to a new report from Johns Hopkins Kimmel Cancer Center in the US. 26 Aug 2014

Type-1 and type-2 diabetes are caused by the same hormone malfunction
New evidence from research at at the Universities of Manchester and Auckland shows that juvenile-onset or type-1 diabetes and type-2 diabetes are both caused by the formation of toxic clumps of a hormone called amylin. 22 Aug 2014

Botox can slow tumour growth
Research at Columbia University Medical Center and the Norwegian University of Science shows that cutting off the nerves to tumours using surgery or Botox can reduce the growth of cancer cells. 22 Aug 2014

Genetic analysis of Candida glabrata shows new genetic sources of drug tolerance
The Max F. Perutz Laboratories in Vienna has coordinated a genetic study of Candida glabrata that has discovered 28 new genes that are partly responsible for the yeast's tolerance of common drugs. 20 Aug 2014

Old drug restores hair in alopecia areata patients
Researchers at Columbia University Medical Center (CUMC) have tested a drug that has eliminated the immune cells attacking hair follicles and restored hair growth in a small number of patients. 20 Aug 2014

Smartphones to be adapted to monitor and manage stress, nutrition and HIV infection
A multidisciplinary team headed by Cornell University has been awarded a $3million grant to combine microfluidics and smartphone technology for health monitoring and improving patient engagement in their healthcare. 20 Aug 2014

Western Sussex Hospitals to install acute kidney disease monitoring system
Western Sussex Hospitals NHS Foundation Trust in southern England is launching a project to monitor patients and alert clinical staff of patients at risk of kidney failure. 19 Aug 2014

Gecko Biomedical's Maria Pereira named as MIT Technology Review Innovator
Gecko Biomedical has announced that Maria Pereira, its Head of Adhesive Technologies, has been named as one of MIT Technology Review's “35 Innovators Under 35” for 2014 for the development of a wound healing glue. 19 Aug 2014

Roche and Garvan Institute of Medical Research partner to develop epigenomics technology
Roche and the Garvan Institute of Medical Research in Australia are collaborating to develop new technologies to accurately analyze regions of the epigenome using DNA sequencing. 19 Aug 2014

Increase in body weight linked to increased risk of 10 cancers
A study following the health of more than 5 million adults in the UK has found that people with a higher body mass index (BMI) have an increased risk of developing 10 of the most common cancers. 14 Aug 2014

New pathology software improves cancer diagnosis
New software developed jointly by the MedUni Vienna and the Vienna-based firm Tissuegnostics helps pathologists to identify cancerous tissue with greater accuracy and remove some of the variability in current methods based on visual analysis of tissue samples. 14 Aug 2014

Scripps labs studying the structure of antibodies to Ebola virus
Laboratories at The Scripps Research Institute (TSRI) are investigating antibodies to fight Ebola virus, including the three experimental antibodies recently used to treat two American health care workers infected with the virus. 13 Aug 2014

Analysis of electronic health records finds effective medicines quicker and cheaper than clinical trials
Analysing electronic health records of large patient populations can efficiently select the right patients and identify the effectiveness of treatments with minimal impact on patients and reduce the need for expensive clinical trials. 13 Aug 2014

Leishmaniasis parasite protects the fly that transmits it to humans
The Leishmania parasite, which causes the human disease leishmaniasis, acts as a probiotic in the insect that transmits it to humans, protecting them from infection by bacteria. 13 Aug 2014

Genetic material of caries bacterium obtained from ancient teeth
Spanish and Mexican researchers sequencing genes of tooth bacterium going back to the Bronze Age have found increased genetic change in recent times, coinciding with dietary change linked to the expansion of humanity. 13 Aug 2014

Inova chooses Avere storage system for managing the world’s largest genome sequence database
Avere Systems has announced that the Inova Translational Medicine Institute (ITMI) has chosen Avere's hybrid cloud storage systems for the world’s largest, centralised repository of whole genome sequence data. 12 Aug 2014

Carestream adds motor assist feature to DRX-Evolution radiography systems
Carestream has added a motor assist feature to its Carestream DRX-Evolution DR Room that allows operators to manually move the overhead tube with assistance from the system’s motors. 12 Aug 2014

Oraya Therapeutics awarded grant to develop gold nanoparticle cancer therapy
Oraya Therapeutics, Inc. has been awarded a US$215,000 Small Business Technology Transfer Grant by the US NIH to investigate how Oraya Therapy can further enhance the treatment of wet age-related macular degeneration. 12 Aug 2014

Rapid Biosensor Systems appoints chair in move to IPO
Cambridge company Rapid Biosensor Systems Ltd has appointed John Reynolds OBE as Executive Chairman to take it to the next stage of growth. 12 Aug 2014

Princess Alexandra Hospital launches electronic patient record system
The Princess Alexandra Hospital NHS Trust in Essex, UK, has gone live with the Cambio COSMIC integrated electronic patient record system across its hospital site, external services and outpatient clinics. 6 Aug 2014

EMIS wins contracts for community care systems in the south of England
EMIS has signed two major contracts under the NHS London and Southern procurement framework to provide its EMIS Web software to community care providers. 6 Aug 2014

Bacteriophages could be new tool to fight C. diff infections in hospitals
A class of viruses called bacteriophages can infect and destroy the bacterium Clostridium difficile, according to research at the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, and published in PLOS Pathogens. 4 Aug 2014

Gut bacteria give accurate diagnosis of liver cirrhosis 
Scientists from the French National Institute for Agricultural Research (INRA) in collaboration with a Chinese team found that the gut microbiota of individuals with liver cirrhosis differ notably from healthy individuals and have a high proportion bacteria common in the mouth. 4 Aug 2014

July 2014

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