Tissue Studio 2.0 supports tumour profiling, multiplexing and biomarker translational research

13 August 2010

Definiens has introduced version 2.0 of its Tissue Studio image analysis software for digital pathology.

The software analyses images for biomarker translational research. In a wide array of different tissue stains, the software automatically and accurately detects and measures cells and sub-cellular components within regions of interest. It provides cell-by-cell quantification of protein expression and describes cellular morphology.

Along with improved processing speed, the new version now includes a full range of functionality for the analysis of immunofluorescence tissue stains. Up to twelve immunofluorescence channels per image are supported. It also includes more accurate nucleus detection.

With its “learn-by-example” format, users train the software to identify representative regions of interest, and configure the software to automatically identify cells and sub-cellular objects. Beside the analysis of whole virtual slides, it also provides full support to process tissue micro arrays. Pathologists do not need prior computer programming, and can develop customized image analysis solutions in as little as 20 minutes.

“The fantastic reception to Definiens Tissue Studio over the last year has demonstrated the growing need among pathologists for accurate biomarker detection and quantification tools. The quality and significance of data generated from tissue slide analyses depend on the accuracy and consistency of the detection tools utilized,” said Martin Baatz, PhD Vice President of Marketing at Definiens.

“With Definiens Tissue Studio 2.0, we are providing an increased level of accuracy and speed while preserving the accessible interface and workflow that has been embraced by our customers.”

"Understanding cell morphologies is central to our work at the Breakthrough Research Unit,” said Elad Katz, Ph.D. at the Western General Hospital at the University of Edinburgh.  “We are extremely impressed with the ability of Definiens Tissue Studio 2.0 to reliably and accurately analyze our immunofluorescence studies, providing detailed morphological information about cell size, length and interrelations to neighboring cellular structures.  We have not encountered any other software able to provide such an accurate and detailed perspective."