Cresset establishes new division to provide computation chemistry
25 March 2010
Cresset has launched Versaphor, a new desktop applications
division aimed at supplying high quality tools based on its molecular
fields technology to a range of markets, including: medicinal chemists,
patent teams (internal and external counsel), pre-clinical safety teams
and in-licensing teams.
Versaphor’s field-based tools enable companies to find smarter
answers to their chemistry questions and make quicker,
better-informed decisions about which molecules deserve investment
of time, effort and capital.
Versaphor’s first products are medicinal chemistry and
patent-specific versions of the FieldStere bioisostere generator.
The Medicinal Chemistry application allows medicinal chemists to
generate highly innovative ideas for drug-like lead molecules in new
areas of chemical space. The Patent application enables patent
attorneys to identify and more accurately evaluate the ‘obviousness’
of new chemical filings and to develop stronger patent filings
covering a wider range of structural diversity.
Cresset’s field-based tools have successfully been used by
computational chemists for over eight years to predict and compare
the activity and properties of their lead compounds. Instead of
relying on 2D structure, Cresset uses the fields around molecules to
assess their likely biological activity and properties, regardless
of structural similarity. Cresset’s fields provide an accurate,
highly-condensed representation of the nature, size and location of
the critical properties required for binding and instigating a
specific therapeutic effect.
“The Versaphor division will develop Cresset’s core technology
into market-specific applications, enabling diverse groups in
pharmaceutical and biotech companies to realise the full benefits of
Field based chemistry” said Bea Leigh, Chief Executive Officer,
Cresset. “We will deliver tailored desktop applications through
Versaphor, whilst continuing to focus on the developing needs of the
computational chemistry market through Cresset.”