Sartorius Stedim Biotech introduces innovative single-use
28 May 2009
Sartorius Stedim Biotech (SSB)(Paris:DIM) has introduced two
prototypes of innovative single-use bioreactors that operate based on
novel mixing technologies. These cell culture systems were developed in
co-operation with the German company Bayer Technology Services GmbH
(BTS) and the Swiss cell culture specialist ExcellGene SA. The new
bioreactors have been specially designed for the manufacture of
monoclonal antibodies, recombinant proteins and vaccines.
So far, Sartorius Stedim Biotech has been offering its customers in
the pharma and biotech industries two types of single-use bioreactor:
the BIOSTAT CultiBag STR product line, which features a stirred tank
design as in conventional reusable bioreactors, and the BIOSTAT CultiBag
RM that uses rocking motion for mixing of cell cultures.
The company plans to extend its technology portfolio by two further
systems by 2010: a rotationally oscillating bioreactor and an orbital
shake bioreactor. Each of these four agitation technologies offers users
specific advantages contingent upon the cells to be produced, the
scale-up level of the cell cultures and additional process parameters.
“Based on this comprehensive technology platform, we are taking a
huge step forward towards achieving our goal of becoming the global
market leader in single-use bioreactors,“ commented Dr Oscar-Werner Reif,
who is responsible for research and development on Sartorius Stedim
Biotech’s Board of Directors, on both partnerships. “Whatever our
customers’ application, we offer the best solution, both technically and
Both partners of Sartorius Stedim Biotech are bringing new
process-optimized cell cultivation technologies, application-enhanced
drive and container technology and biological evaluation of the new
bioreactors into these cooperative alliances.
Sartorius Stedim Biotech provides its expertise in disposable
cultivation vessels and bags as well as single-use sensor technology and
supplies the bioreactor control system, BIOSTAT, for controlling the new
bioreactors. Today, BIOSTAT is already the global benchmark in the
market for conventional, reusable bioreactors.
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