First Dräger Award for Intensive Care Medicine bestowed
13 June 2007
Lübeck, Germany. The European Society of Anaesthesiology
(ESA) has presented the first Dräger Award for Intensive Care Medicine to
the Department of Anaesthesiology and Intensive Care Medicine at the
Friedrich Schiller University in Jena, Germany.
The award was presented at the Society's annual congress, Euroanaesthesia
2007, in Munich. The €10,000 endowment
was donated by Dräger Medical AG & Co. KG.
The award went to the working
group studying ventilation-associated lung injury in the Department of
Anaesthesiology and Intensive Care Medicine at the University (1).
The Scientific Programme Committee of ESA who judged the prize recognized
the working group for their investigation, which was published in the paper,
Increased Susceptibility to Ventilator associated Lung Injury Persists
after Clinical Recovery from Experimental Endotoxemia (2).
opening ceremony, Sir Peter Simpson, President of the ESA, together with
Helge Hussy, General Manager of Dräger Medical Deutschland GmbH, presented
the award to Dr Lars Hüter, representing the working group.
This annual prize honours significant research in the field of intensive
care medicine published in peer-reviewed intensive care or anaesthesiology
journals in the preceding year. The prize is given to the institution that
produces the article rather than any one research worker.
The award recipients, Dr Schreiber's working group in Jena, has been
conducting experiments for a number of years in the field of
ventilation-induced or ventilation-associated lung injury. In complex
in-vivo models, the working group has studied the factors and conditions
influencing the damaging effects of artificial ventilation (3). Clinically
relevant situations are simulated, with the study concentrating on the
effects of different ventilation parameters (eg tidal volume or PEEP level)
on the pulmonary and systemic inflammatory response.
demonstrated that even after recovery from a transient period of
endotoxemia, susceptibility to the deleterious effects of increasing tidal
volumes increases over time. This suggests that lower tidal volumes, already
known to protect patients with acute respiratory distress syndrome (ARDS)
are also of benefit after full clinical recovery from the inflammatory
As Chairman of the Dräger Prize Subcommittee, Prof Jennifer M.
MB ChB PhD FRCA, School of Clinical Science (Anaesthesia), University
of Liverpool, UK, stated that this paper was selected as it showed the
highest standard of scientific study of all the submissions, with results
that were most likely to affect future clinical practice.
1. Head of the working group: Dr Torsten Schreiber;
members: Dr Lars Hüter, Dr Konrad Schwarzkopf, all of the Hospital for
Anaesthesiology and Intensive Care Medicine at the Friedrich Schiller
University in Jena and PD Dr Waheedullah Karzai, Deptm. of Anaesthesia,
Zentralklinik Bad Berka GmbH.
2. First published in Anesthesiology
2006, 104: 133–41.
- Schreiber T, Hüter L, Gaser E, Schmidt B, Schwarzkopf K, Karzai W.
Effects of a catecholamine-induced increase in cardiac output on lung
injury after experimental unilateral pulmonary acid instillation.
Crit Care Med. 2007 May 22. epub ahead of print;
- Schreiber T, Swanson PE, Chang KC, Davis CC, Dunne WM, Karl IE,
Reinhart K, Hotchkiss RS. Both gram-negative and gram-positive
experimental pneumonia induce profound lymphocyte but not respiratory
epithelial cell apoptosis. Shock. 2006 Sep; 26(3): 271-6.;
- Schreiber T., Niemann C., Schmidt B., Karzai W.: A novel model of
selective lung ventilation to investigate the long-term effects of
ventilation-induced lung injury. Shock. 2006 Jul;26(1):50-4.;
- Schreiber T, Hüter L, Gaser E, Schmidt B, Schwarzkopf K, Rek H,
Karzai W: PEEP has beneficial effects on inflammation in the injured and
no deleterious effects on the non-injured lung after unilateral lung
acid instillation. Intensive Care Med. 2006 May;32(5):740-9