Trial of gastric electrical stimulation for treatment of obesity
in diabetes patients
19 August 2005
Medtronic has announced that it is conducting a feasibility trial, called
ASSIST (Appetite Suppression Induced by Stimulation Trial), to test the
safety and efficacy of gastric electrical stimulation (GES) for the
treatment of obesity in patients with type 2 diabetes. The first implant
occurred June 7, 2005, at Scripps Memorial Hospital La Jolla, in San Diego.
Dr. Mark Sherman performed the implant of the gastric stimulator and two
stimulation leads. The leads, or wires, are implanted into the wall of the
stomach via laparoscopy.
The ASSIST trial is designed to determine if type 2 diabetes patients
with concomitant obesity who receive gastric electrical stimulation have a
minimum mean excess weight loss greater than a control group. The trial will
evaluate excess weight loss and glycaemic control. The feasibility trial
will take place in a small number of select centres in the United States.
"Gastric electrical stimulation could be a solution that provides
treatment options for weight loss and subsequent reduction of type 2
diabetes mellitus," said Dr. Daniel Einhorn, an endocrinologist and
principal investigator at Scripps La Jolla. "This study brings a
multi-disciplined approach to obesity and diabetes management, and provides
the opportunity to improve management with other therapeutic and surgical
options for obesity."